2034 Acute Reduction of Lipoprotein ( a ) by Tissue - Type Plasminogen Activator
نویسندگان
چکیده
Background. Lipoprotein(a) [Lp(a)] is a low density lipoprotein-like particle whose apolipoprotein B (apo B) moiety is disulfide-linked to apo(a), a plasminogen-like inhibitor of fibrinolysis in vitro. We hypothesized that plasma concentrations of Lp(a) are acutely affected by intravenous tissue-type plasminogen activator (t-PA). Methods and Results. Patients with unstable angina were randomized to receive either intravenous t-PA (n= 15) or placebo (n =11). Two-way ANOVA using repeated measures revealed a significant effect of t-PA
منابع مشابه
Acute reduction of lipoprotein(a) by tissue-type plasminogen activator.
BACKGROUND Lipoprotein(a) [Lp(a)] is a low density lipoprotein-like particle whose apolipoprotein B (apo B) moiety is disulfide-linked to apo(a), a plasminogen-like inhibitor of fibrinolysis in vitro. We hypothesized that plasma concentrations of Lp(a) are acutely affected by intravenous tissue-type plasminogen activator (t-PA). METHODS AND RESULTS Patients with unstable angina were randomize...
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تاریخ انتشار 2005